Research Statement.
Designing novel computational algorithms and tools to improve cancer patients’ health by triggering the genetic, genomic, epigenomic, and environmental factors and connecting the molecular dots and genetic differences in the population to develop the most effective, less toxic, and patient-specific therapies.
Skills
First-author publication track-record
Expertise in the genetic and biological principles to guide the analyses and interpretation of New Generation Sequencing data
Expertise in working with genotyping and gene sequence data including quality control and association analyses with clinical phenotypes
Expertise in bioinformatics, statistical genetics, biostatistics, and computational biology
Expertise in supervised and unsupervised machine learning methods
Experience in network science methods
Programming skills in R, MATLAB, Python, Shell, and Bash scripts, expertise with documentation, version control, and code releases
Experience in Big data platforms like Hadoop, Hive, Impala, SparklyR
Expertise in Parallel Computing and Linux-based High-Performance Computing
Extensive training in mathematics and statistics including demonstrated teaching experience
Education
Marquette University, Milwaukee: Ph.D. in Computational Sciences (Sep 2015-May 2021)
University of Wisconsin, Milwaukee: MS in Mathematics (2013-2015)
Visva Bharati University, India: Bachelor and Master of Science in Physics (B.Sc. + M.Sc.)
Positions held
Feinberg School of Medicine, Department of Genetic Medicine, Northwestern University, Chicago, IL
Postdoctoral Research Scientist
Bioinformatics Lab, Department of Mathematical and Statistical Sciences, Marquette University, Milwaukee, WI
Research Assistant
Department of Mathematical and Statistical Sciences, Marquette University, Milwaukee, WI
Teaching Assistant
Courses Taught: Modern Elementary Statistics, Calculus I, II, III
Northwestern Mutual, Milwaukee, WI
Data Scientist (Intern)
Department of Mathematical and Statistical Sciences, Marquette University, Milwaukee, WI and Milwaukee Institute (High Performance Computing)
Teaching Assistant; Data Scientist (Intern)
Courses Taught: Calculus I, II
Department of Mathematical Sciences, University of Wisconsin-Milwaukee, WI
Teaching Assistant
Courses Taught: Undergraduate Algebra and Calculus
Awards
Computational Sciences Summer Research Fellowship Award, Marquette University, 2020 $5,000
Fellowship award for attending ISMB 2020, VIRTUAL $150
NSF travel fellowship for International Workshop on Computational Network Biology:
Modeling, Analysis, and Control (CNB-MAC 2019) $400
NSF travel fellowship for Conference on Bioinformatics, Computational Biology,
and Health Informatics (ACM BCB 2019) $1,000
Northwestern Mutual Data Science Institute Research Fellowship Award, Summer 2019 $3,500
Northwestern Mutual Data Science Institute Research Fellowship Award, Spring 2019 $5,000
NSF Travel fellowship for GLBIO (Great Lakes Bioinformatics Consortium), 2019 $250
Computational Sciences Summer Research Fellowship Award, Marquette University, 2018 $5,000
Computational Sciences Summer Research Fellowship Award, Marquette University, 2016 $5,000
University of Wisconsin Milwaukee Chancellors Fellowship, 2013: Top MS student award $2,000
University of Wisconsin Milwaukee Chancellors Fellowship, 2014: Top MS student award $2,000
First Author Publications
Banabithi Bose and Serdar Bozdag. 2020. CTDPathSim: Cell line-tumor deconvoluted pathway-based similarity in the context of precision medicine in cancer. In Proceedings of the 11th ACM International Conference on Bioinformatics, Computational Biology and Health Informatics (BCB '20). Association for Computing Machinery, New York, NY, USA, Article 7, 1–10. https://doi.org/10.1145/3388440.3412456
Bose, B., Moravec, M. & Bozdag, S. Computing microRNA-gene interaction networks in pan-cancer using miRDriver. Sci Rep 12, 3717 (2022). https://doi.org/10.1038/s41598-022-07628-z
Bose, B., Moravec, M & Bozdag, S. (2022). Computing microRNA-gene interaction networks in pan-cancer using miRDriver. https://doi.org/10.21203/rs.3.rs-1101651/v1 (preprint)
Posters and talks
Two poster presentations at ISMB (Intelligent Systems For Molecular Biology), Virtual Conference (2020) Title 1: CTDPathSim: Cell line-tumor deconvoluted pathway-based similarity in the context of precision medicine in cancer. Title 2: miRDriver: A computational tool to infer copy number derived miRNA-gene networks in cancer.
Poster presentation at Forward Thinking Colloquium, Marquette University, Milwaukee, WI (2019) Title: PDDRNet_MH: Patient-Derived Drug Response using Multiplex Heterogeneous Networks.
Poster presentation at GLBIO (Great Lakes Bioinformatics Consortium) (2019) Title: miRDriver: A computational tool to infer copy number derived miRNA-gene networks in cancer.
Colloquium talk in Department of Mathematics, Statistics, and Computer Science, Marquette University, Milwaukee, WI (2019) Title: miRNAdriver: Copy Number Derived microRNA-Gene Interactions in Cancer.
Poster presentation at ECCB (European Conference on Computational Biology) (2018) Title: Copy Number-Derived microRNA-Gene Interactions in Cancer.
Poster presentation at Forward Thinking Colloquium, Marquette University, Milwaukee, WI (2017) Title: An integrated framework for identifying context-specific gene-drug interactions among cancer patients: An advanced step towards personalized medicine.
Talk in Northwestern Mutual Insurance Company, Milwaukee, WI (2017) Title: DART(Digital Analytics and Research Team) Cloudera Hadoop Implementation: Proof of concept.
Talk in Northwestern Mutual Insurance Company, Milwaukee, WI (2017) Title: Measuring client effort through Digital analytics.
Presentation in Statistical Seminar, Marquette University, Milwaukee, WI (2016) Title: Introduction of spatial correlation in healthcare insurance data.
Presentation in Applied Mathematics Talk, Marquette University, Milwaukee, WI (2015) Title: Principal Component Analysis.
Presentation in Applied & Computational Mathematics Seminar, UW-Milwaukee, WI (2015) Title: A study on the blood-tissue exchange model and its algorithm.
Additional Activities
Mentoring undergraduate research assistants in bioinformatics, data science, and computer science
Sub Reviewer of ISMB/ECCB (Intelligent Systems for Molecular Biology/ European Conference on Computational Biology)
2019 submissions Sub Reviewer of GIW (International Conference on Genome Informatics) 2018 submissions
Sub Reviewer of BCB (Bioinformatics and Computational Biology) 2018 submissions
Served as an active member of ACM-Women chapter at Marquette University, Milwaukee, WI